产品货号：
Z36912
中文名称：
IDE抗体
英文名称：
Anti-IDE Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-IDE Antibody |
| 指标别名 | Abeta degrading protease;IDE;INSULYSIN |
| 克隆性 | Monoclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | WB,IHC |
| 基因名称 | IDE |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | A synthesized peptide derived from human IDE |
| 实际分子量 | 118KD |
| 成分 | 500μg/mL;Rabbit IgG in phosphate buffered saline,pH7.4,150mM NaCl,0.02% sodium azide and 50% glycerol. |
| 纯化方式 | Affinity-chromatography |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | Insulin-degrading enzyme,also known as IDE,is an enzyme.This gene encodes a zinc metallopeptidase that degrades intracellular insulin,and thereby terminates insulins activity,as well as participating in intercellular peptide signalling by degrading diverse peptides such as glucagon,amylin,bradykinin,and kallidin.The preferential affinity of this enzyme for insulin results in insulin-mediated inhibition of the degradation of other peptides such as beta-amyloid.Deficiencies in this protein's function are associated with Alzheimer's disease and type 2 diabetes mellitus but mutations in this gene have not been shown to be causitive for these diseases.This protein localizes primarily to the cytoplasm but in some cell types localizes to the extracellular space,cell membrane,peroxisome,and mitochondrion.Alternative splicing results in multiple transcript variants encoding distinct isoforms. |
| Uniprot ID | P14735 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P).*Blocking peptide可以联系我们购买。 |
| 基因名全称 | Insulin-degrading enzyme |
| 推荐稀释比 | Western blot (WB) 1:500～2000 Immunohistochemistry in paraffin section (IHC) 1:20～100 |
相关搜索：IDE抗体，IDE单抗，Anti-IDE Antibody